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Superoxide dismutase [Mn], mitochondrial structure
P04179
SODM_HUMAN
SOD2

Superoxide dismutase [Mn], mitochondrial

Homo sapiensTaxon: 9606

3D-structureAcetylationAlternative splicingDirect protein sequencingManganeseMetal-bindingMitochondrionNitrationOxidoreductaseProteomics identificationReference proteomeTransit peptide+1
序列长度

222

氨基酸

分子量

24.8 kDa

理论值

实验结构

48

PDB 条目

相关疾病

1

已记录

功能描述

Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems

相关疾病

Microvascular complications of diabetes 6

Pathological conditions that develop in numerous tissues and organs as a consequence of diabetes mellitus. They include diabetic retinopathy, diabetic nephropathy leading to end-stage renal disease, and diabetic neuropathy. Diabetic retinopathy remains the major cause of new-onset blindness among diabetic adults. It is characterized by vascular permeability and increased tissue ischemia and angiogenesis.

氨基酸序列

MLSRAVCGTSRQLAPVLGYLGSRQKHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVN
NLNVTEEKYQEALAKGDVTAQIALQPALKFNGGGHINHSIFWTNLSPNGGGEPKGELLEA
IKRDFGSFDKFKEKLTAASVGVQGSGWGWLGFNKERGHLQIAACPNQDPLQGTTGLIPLL
GIDVWEHAYYLQYKNVRPDYLKAIWNVINWENVTERYMACKK

FASTA 格式 · 222 个氨基酸 · 分子量 24.8 kDa