知识库首页
Serine protease 1 structure
P07477
TRY1_HUMAN
PRSS1

Serine protease 1

Homo sapiensTaxon: 9606

3D-structureCalciumDigestionDirect protein sequencingDisease variantDisulfide bondHydrolaseMetal-bindingProteaseProteomics identificationReference proteomeSecreted+4
序列长度

247

氨基酸

分子量

26.6 kDa

理论值

实验结构

12

PDB 条目

相关疾病

1

已记录

功能描述

Has activity against the synthetic substrates Boc-Phe-Ser-Arg-Mec, Boc-Leu-Thr-Arg-Mec, Boc-Gln-Ala-Arg-Mec and Boc-Val-Pro-Arg-Mec. The single-chain form is more active than the two-chain form against all of these substrates

相关疾病

Pancreatitis, hereditary

A disease characterized by pancreas inflammation, permanent destruction of the pancreatic parenchyma, maldigestion, and severe abdominal pain attacks.

氨基酸序列

MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVS
AGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVIN
ARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKIT
SNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIK

FASTA 格式 · 247 个氨基酸 · 分子量 26.6 kDa